Vitamin K: High Doses of MK-4 and MK-7 Show Promising Results

Posted by daisy17 @daisy17, Apr 7 12:07pm

It seems as though doctors in the U.S. focus primarily on medications to treat osteoporosis, many of which have undesirable side effects.

I find it curious that doctors never seem to mention taking high doses of Vitamin K, which has few side effects and has shown promising results in Japanese studies that indicate vitamin K2, specifically MK-4 and MK-7, may improve bone health. MK-4 has been prescribed for osteoporosis in Japan because studies there showed it had benefits in bone density and strength.

Based on this information, I recently started taking 180mcg of Menaquinone-7 (MK7) TrueVantage brand and 45,000 mcg (45 mg) of vitamin K2 (menaquinone-4) - Life Extension K2 High Potency brand.

AI Assist says that it's okay to take both forms: “Taking vitamin K2 in both MK-4 and MK-7 forms together can be beneficial, as they have different properties and roles in the body. MK-4 has a shorter half-life and is quickly metabolized, while MK-7 has a longer half-life and remains active for a longer period, supporting continuous bone and cardiovascular health. Combining both forms may provide comprehensive support for bone health and calcium metabolism.”

Here are a couple articles on this: https://naturalhealthresearch.org/vitamin-k2-and-bone-loss/
https://www.lifeextension.com/magazine/2022/3/bone-loss-vitamin-k-high-dose

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

Profile picture for tkdesign @tkdesign

I'm trying a higher dose vitamin K also, because I've been unable to tolerate any other osteoporosis drug and have severe disease. At this point it's my only hope. If the drs won't acknowledge it as being studied and a real treatment, then I will try my own way. All they know is pharma. I think they make their money steering patients to certain drugs.

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@tkdesign I am trying it also. But I don't have hopes that it will improve my DEXA scores, I just hope they would at least not decline any further. Exercise is important too. I love the free video's on Facebook under Brick House Bones by Dr Lisa Moore, a P.T. who specializes in osteoporosis.

I don't know that doctors make money steering patients to drugs, I think they are only following drug protocols established by medical organizations and regulatory agencies.

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Profile picture for ipg @ipg

I take 180mcg of mK7 which converts to Mk4. Supposedly that’s enough. Because of Mk4 short life 5mg tablets dispersed 3x through the day should be enough

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@ipg
I take 180of my-7 and 400ius if D3 my endocrinologist tests D3! Yearly. She said that’s enough for me

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Does anyone use the vitamin k and d s as previously posted and calcium supplements.
I have osteoporosis and severe atherosclerosis🙁

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Profile picture for daisy17 @daisy17

@julieilic Yes, you may also need D3 supplements. It's included in many calcium supplements. Attached article says "Pair K2 with Vitamin D3: D helps absorb calcium; K2 helps direct it into bones (and away from soft tissues)."
https://betterbones.com/bone-health-basics/vitamin-k2-mk7-vs-mk4/

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@daisy17
Yes thanks..definitely..I also do mk7 dr as per the Japanese study on mayo clinic osteoporosis group as I also have stage 4 osteoporosis and unfortunately multiple other things going on. Ugh.

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Typo: and D3 (not dr lol )

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Profile picture for julieilic @julieilic

@daisy17
Yes thanks..definitely..I also do mk7 dr as per the Japanese study on mayo clinic osteoporosis group as I also have stage 4 osteoporosis and unfortunately multiple other things going on. Ugh.

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@julieilic I also take MK-7 and MK-4. I didn't know osteoporosis was classified in stages...what does stage 4 mean?

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Profile picture for hurstka @hurstka

Does anyone use the vitamin k and d s as previously posted and calcium supplements.
I have osteoporosis and severe atherosclerosis🙁

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@hurstka Yes, I originally posted this discussion comment about the two forms of vitamin K. I also take calcium supplements, alternating between types (algae based, Citrical, and calcium carbonate). I take one Seen Calcium Chew, which is food sourced. And I take Vitamin D every other day or so since it's included in my calcium supplements. Plus Algae Cal collagen supplement and magnesium glycinate.

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Profile picture for daisy17 @daisy17

@julieilic I also take MK-7 and MK-4. I didn't know osteoporosis was classified in stages...what does stage 4 mean?

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@daisy17
Stage 4 (severe) osteoporosis is the most advanced stage of the disease, defined by a bone mineral density T-score of -2.5 or lower alongside at least one prior fragility fracture.

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