Is anyone taking Nuzyra for M. Abscesses or other?

Posted by kathyjjb @kathyjjb, May 5 10:57am

Nuzyra is a new antibiotic used to treat M. Abscesses. It should be taken after 4 hours of fasting and prior to 2 more hours of fasting. I decided to take at 10 PM, but now I can't sleep. Insomnia is a side effect. I'm taking Linezolid at 6 AM and 6 PM, and Arikayce at 11 AM. Since I want to space out my drugs, now thinking on changing my time. Anyone else having or had this issue? Did the insomnia subside? I'm thinking set alarm for maybe 3 AM and take then? I'm doing good with Linezolid taking with toast in the morning and dinner at night. Though Linezolid is complicated too, since diet should be low or void of Tyramines to help avoid side effects.

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Profile picture for kathyjjb @kathyjjb

I'm curious if anyone with M.Abscessus and has Medicare Advantage plan been approved for Nuzyra? Though, I am now testing negative for MABC, my ID doctor told me recurrence/reinfection is 50%. My current Medicare Advantage plan denied coverage last May for Abscessus. Also, my insurance broker told me that Bronchiectasis is an exclusion for Medigap, so at this time and unless things change, I'm stuck with Medicare Advantage. I have since learned that Nuzyra is not considered a standard treatment for MABC. which gives the insurance company a loophole in denying coverage. I'm trying to stay vigilant to avoid reinfection.

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@kathyjjb I have traditional Medicare Supplement Medical Mutual and my script plan is WellCare. WellCare has covered Nuzyra and inhaled Arikayce. My ID had to complete extensive request information. Can you switch to traditional from advantage and choose a script plan?

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Profile picture for peterstl @peterstl

Hello: I was diagnosed with Mycobacterium Abscesses in September 2024. I started IV Amikacin, Azithromycin and Omadacyclin in June 2025. I started to get a loud ringing in my right ear after being on the IV Amikacin for 7 weeks. I was taken off the IV Amikacin in August. The ringing did not go away. Is there any treatment that can reverse of repair the damage caused by Amikacin? Are there medications or supplements that have shown any benefit for drug induced tinnitus? Has anybody else experienced this?

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@peterstl

Hi, I have been treated for Abscsses since June 2025. Recently taken off IV Amikacin because it causes permanent hearing loss. On Nuzyra, Clatithromycin, Aryikayce and Brinsupri. ID doc getting insurance approval for another oral pill. I am not getting better. In fact maybe worse. Is anyone short of breath, coughing and bringing up mucus all day long and on oxygen 24/7?

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Profile picture for rizzinator @rizzinator

@peterstl

Hi, I have been treated for Abscsses since June 2025. Recently taken off IV Amikacin because it causes permanent hearing loss. On Nuzyra, Clatithromycin, Aryikayce and Brinsupri. ID doc getting insurance approval for another oral pill. I am not getting better. In fact maybe worse. Is anyone short of breath, coughing and bringing up mucus all day long and on oxygen 24/7?

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@rizzinator
I am sorry to hear that you are not getting better. Do you have an ID doctor at Mayo? Mayo seems to know the combination of drugs that can help to battle this. When I was taken off the Amikacin due to the hearing loss, I was put on an IV antibiotic called Imipenem. I will not regain my hearing, I am told.
Please keep me updated.

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Profile picture for janetannfaust @janetannfaust

@kathyjjb I have traditional Medicare Supplement Medical Mutual and my script plan is WellCare. WellCare has covered Nuzyra and inhaled Arikayce. My ID had to complete extensive request information. Can you switch to traditional from advantage and choose a script plan?

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@janetannfaust Thank you for the info. Unfortunately, I cannot get a Medigap plan due to my Bronchiectasis or so I have been told by my insurance broker. I sure hope I keep testing negative.

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