Hi, 40m here. Sorry to hear of your ailments. I have been experiencing something very similar since Sept 5. Pressure is mostly in my forehead area. It has been constant and varying in severity but its always there. Then came the waves of "anxiety" just a feeling of immense mental discomfort. Complete lack of appetite or any desire at all. Stomach discomfort constipation, insomnia, breathless when talking, and a host of others. My last trip to urgent care they gave me some cocktail that included toradol. I felt pretty good for like 24 hours before it came back. It has been much less severe and thankfully has not returned to the previous extremes. Thinking the toradol helped, I began taking 800mg ibuprofen daily and they seemed to really help. Able to eat and sleep much better but still no appetite. Even a few moments where i acrually felt good, like myself but they came by and went quickly. They were a nice reminder of how things were tho. Triptans did nothing. Brain mri clean. Sinus ct showed some inflammation and a possible csf leak, but ent said it looked OK and my nose isnt usually running. Neuro has me on a course of prednisone right now, 60mg seem to have a similar effect as the ibuprofen, but the pressure is still constant but the other symptoms are very quiet. Gi had no answers, acupuncture and herbal extracts, vitamins, supplements, and still at a loss. I do vape and I cleaned my shower with bleach before symptoms began but still struggling to find anything else that effects the pressure one way or another. I will be sure to keep you updated if anything else and please do the same. Best of luck to you in your search.