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Started Repatha - Side Effects

Heart & Blood Health | Last Active: 6 days ago | Replies (441)

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Profile picture for HomeAgainLA @llynch17056

God bless you. It’s not your imagination. My cardiologist was amazingly unaware of the symptoms (just as you described them) caused to some by all the medications you mentioned, including Repatha. When I couldn’t get out of bed (and I am a very active person) I had to stop the Repatha. My cardiologist blew me off. Some people have no side effects, others, like you and I, have debilitating side effects. My cardiologist seemed to think I was either faking the side effects or exaggerating them. His attitude was to take these medications no matter how sick they made me. It took much longer for the Repatha symptoms to leave my body than it took the various statins. I ultimately decided that I would rather live a shorter life and be happy and active than to live bed bound by a drug. And, I was concerned about what I was putting my body through each time I tried another one. Right now I am on Terzepitide with no side effects. (It is not a statin). It has potential to lower LPL. I will test again in a couple of months (after 6 months on it). I am going to report back here. At this point in my life I am skeptical about the numbers obsession especially when the “cure” for high numbers are drugs that make me sick. I’m old enough to have witnessed drugs come and go, one day they are miracle makers and the next they will kill you (statins feel like killers). My internist told me to quit worrying about it. He said I’m active, eat healthy and I’m enjoying my life. He also points to my 3.5 ratio.

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Replies to "God bless you. It’s not your imagination. My cardiologist was amazingly unaware of the symptoms (just..."

@llynch17056 Thank you for the reply. I have read your previous posts as well. I'm just at a loss. Due for 9th injection today, but I'm not going to do it. I was really surprised by my cardiologist's response; even my PCP said Repatha could cause muscle problems, but not as bad as statins, whereas, cardiologist is saying there's no connection. He is in a reputable group, and as I said, I have really liked him. I am thinking I need a second opinion (from another cardiologist) if he insists I continue to take Repatha (which, right now, I'm thinking I'm not going to).

To be honest, I am quite dejected about it. Thank you for your kind response.

@llynch17056
Whats the 3.5 ratio?

@llynch17056
I, too, have a 3.6 ratio and knew I needed to stop after one injection (symptoms listed above). I decided to start pravastatin but at a 10 mg dose. I am in my early 80’s and found a NIH paper that indicated the “elderly” do well on a smaller dose. I will keep you all posted. The Repatha did get my LDL down into the mid 50’s but at the expense of making my lungs more vulnerable. The statin did not do that.

Shared files

The effectiveness and safety of low dose pravastatin in elderly hypertensive hypercholesterolemic subjects on antihypertensive therapy - PubMed (The-effectiveness-and-safety-of-low-dose-pravastatin-in-elderly-hypertensive-hypercholesterolemic-subjects-on-antihypertensive-therapy-PubMed.pdf)