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← Return to Tymlos side effects
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Osteoporosis & Bone Health | Last Active: Jan 27 11:26am | Replies (107)
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@osteopatient2026 Prolia suppresses the bone-breakdown cells (osteoclasts). If Prolia is stopped, those osteoclasts return with a vengeance: the “rebound effect”. You can lose all your bone density gains, and even end up worse than you were before.
The anabolics like Tymlos, Forteo, and Evenity work on the other side of the equation: they stimulate the bone-building cells (osteoblasts.) You still need to follow up with a biphosphonate, but the potential loss of density without a follow-up is not as severe as with Prolia.
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@njx58
That’s what I was told too. Having problem with Tymlos pre authorization from doctors staff. The insurance said they have sent several requests and not received a response…we went to the doctors office directly instead of calling and played the recording of the insurance rep saying we requested PA but have received anything from your doctor so you were denied. The doctors staff says they sent in the PA.
So the diisays you could always go on Prolia instead it’s authorized under part b. Makes no sense not to use a bone builder first. Exasperated…