@twhite33
My prebiopsy PSA level was 7.8 and has averaged 5.9, over the two years I have been implementing my "aggressive AS protocol". My most recent PSA level was 5.76 (a 26% reduction).

My prebiopsy mpMRI indicated three lesions, one PIRADS 3, one PIRADS 4 and one PIRADS 5. A 12 month follow-up mpMRI indicated that the the PIRADS 3 & 4 lesions were not visible and the PIRADS 5 lesion was smaller and its T2 & DWI signals were reduced from "moderate" to "mild". The same radiologist reviewed and compared both sets of images.

Also, my VO2 Max, a measure of cardiovascular fitness, (see attachment) increased from 39.5 to 49.5, over the two years I've been implementing my program.

All this doesn't prove my program was the cause of these results; however it's entirely consistent with the conclusions reported in the ERASE randomized clinical trial, which found:

“The ERASE trial demonstrated that HIIT increased cardiorespiratory fitness levels and decreased PSA levels, PSA velocity, and prostate cancer cell growth in men with localized prostate cancer who were under active surveillance.”

From my POV, as a retired chemical engineer, the evidence has been convincing enough that I'm sticking with the program 🙂