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Anyone have ET and on Pegasys instead of Hydroxyurea?
Blood Cancers & Disorders | Last Active: Oct 16 7:24pm | Replies (6)Comment receiving replies
Hi @chocolategirl. While you’re waiting for others share their experience with Pegasys (Peginterferon alfa-2a), I did a little search for discussions mentioning Pegasys for you. Here’s one of the links to a conversation that might be helpful.
https://connect.mayoclinic.org/discussion/new-to-pegasus-advice-please/
I’m sorry to hear you’re feeling so miserable on the Pegasys. Are your liver enzymes improving with the lower frequency of the Pegasys injections? Were there signs the ET was progressing while taking the Hydroxyurea?
Replies to "Hi @chocolategirl. While you’re waiting for others share their experience with Pegasys (Peginterferon alfa-2a), I did..."
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@loribmt
Thanks for the link - so kind of you. And yes, my liver enzymes were ok after the switch to 4 weeks for the first time in 5 months. My ET wasn't necessarily progressing but my TP53 mutation went from 30% mutated to 67% in just a few months. Making the switch was to help prevent progression since the TP53 genes is the guardian gene that protects against cancer.