I have been on Orgovyx since JUly 11, 2025. Youbegin with 3 pills first day...then one daily. The first month was kinda tough for me..but once you hit 4th or 5th week..it is no big deal..except :
HOT FLASHES> you will learn they are not much fun- mind dont last long..but are a bit of a nuisance- you will prob have 3-6/day..
Fatigue : a bit but not debilitating...
Sleep: a bit of a problem..I dont sleep as well on ADT.
Appetite: wasnt as hungry early on but that went away.
Dpression: I didn really have tdepression, just was bummed I had cancer..you deal with it..
Hydrate: early on with Orgovyx, I think hydration is very important !

I really think you will find it is pretty tolerable with minimal side effects..- just be aware first 30 days or so are a bit tough.

(Note: Jeff has been on it way longer than me..so I would note his exp as gospel !)