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How fast does Orgovyx work to reduce PSA?
Prostate Cancer | Last Active: Sep 14 5:23pm | Replies (19)Comment receiving replies
in reference to "...then you will probably stay on ADT therapy 1-2 yrs." (Context G8 'High risk of mets)
https://dailynews.ascopubs.org/do/artificial-intelligence-derived-biomarker-may-help-reduce-adt-treatment-duration-some
Skinny on the attached:
Biomarker positives identified by MMAI showed some risk reduction benefit in long term use of hormone deprivation [LTADT/LADT] versus short term
[4-6 months] hormone deprivation [STADT/SADT]
NOTED limit: the data preceded the recent < 3 yr general use of PSMA PET/CT scans. IMHO a G8 or 9 pre 'scans' may harbor more extracapsular prostate extension (ECE) . The 'significant' but only modest difference was beneficial to biomarker positives with LADT. If scanned negatives might have been excluded
it begs the question if the 'significance' might have dropped to a margin of error range borrowing from social science.
Replies to "in reference to "...then you will probably stay on ADT therapy 1-2 yrs." (Context G8 'High..."
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I have been on ORGOVYX 2 months- went from PSA of over 50 to PSA of .05 in 6 weeks or so..doc wants me to start Nubeqa now since I could not tolerate Erleada ( 9 dyas and quit it) ...so I am wondering if stopping ADT in 9 mos.might be as effective as 1 -2 yr...and if Cancer returns, maybe it will still be responsive to ADT therapy
The current protocol is throw everyhting at aggressive prostate cancer early on ( ADT for 12-24 mos + radiation) and hope for long period of remission/"cure"
Lots of guys on here who have been in this war for 5-10 yrs and know alot more than me..I can imagine a recurrence is pretty shattering...like being parolled for many yrs, then returened to prison.