Replies to Here’s a 2014 paper about Perineural Invasion in the Absence of Malignancy —> https://pmc.ncbi.nlm.nih.gov/articles/PMC4772935/#:~:text=Perineu...

← Return to Perineurial invasion. 1 out of 10 samples cancerous. Treatment?

Discussion

Perineurial invasion. 1 out of 10 samples cancerous. Treatment?

Prostate Cancer | Last Active: Jun 5, 2025 | Replies (25)

Comment receiving replies

@brianjarvis

Here’s a 2014 paper about Perineural Invasion in the Absence of Malignancy —> https://pmc.ncbi.nlm.nih.gov/articles/PMC4772935/

There are a number of papers about this.

Jump to this post

Replies to "Here’s a 2014 paper about Perineural Invasion in the Absence of Malignancy —> https://pmc.ncbi.nlm.nih.gov/articles/PMC4772935/#:~:text=Perineural%20invasion%20(PI)%20is%20typically,4%2C5%2C6%5D There are..."

heavyphil | @heavyphil | Jun 1, 2025

I never stop learning on this Forum…funny that older papers mention PNI in the presence of PCa as being very significant for LETHAL outcomes. Yet, articles from 2022 forward, coupled with Dr Epstein’s remarks (cited by @breadmaker) show only marginal significance at worst. Amazing how you can have such diametrically opposed views on the same subject.
And these are not findings culled from bogus websites, but NIH and university research studies…
Phil

VIEW AND REPLY