I am 69 years old and have had depression for over 25 years. I am also on venlafaxine I take 375 mg a day no side effects. It usually works very well but then I do have episodes of depression that come back and I’m at a loss as to what to do. Then my psychiatrist has given me clonazepam to help with the anxiety that I occasionally get for the most part it’s the venlafaxine.