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@mxyzptlk32

From the NCBI article referred to in previous post, under the heading Co-morbid Sleep Disorders, 1st paragraph
"Causes of excessive daytime sleepiness (EDS) in patients with epilepsy may include nocturnal seizures, sedative effects of AEDs, poor sleep hygiene, and co-morbid primary sleep disorders.41 Patients with epilepsy that have EDS should be evaluated for a concurrent primary sleep disorder, which may worsen a patient's seizure burden."

From the last line 2nd paragraph, same heading and article,
"Co-morbid primary sleep disorders should be aggressively sought and treated to achieve optimal management in patients with epilepsy and EDS.43–46"

From the last line last paragraph, same heading and article,
"One recent study suggests that the level of benefit toward seizure reduction provided by nasal CPAP treatment in epilepsy patients with co-morbid OSA is comparable to the effect of adding on an adjunctive antiepileptic drug for seizure treatment; approximately 50–60% of patients experienced a 50% or greater seizure reduction.50"

OSA-Obstructive Sleep Apnea
AED-Anti Epileptic Drugs

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Replies to "From the NCBI article referred to in previous post, under the heading Co-morbid Sleep Disorders, 1st..."

The NCBI article has a section devoted to "Seizures and Antiepileptic Drug Therapies Fragment Sleep" and says in part,

"Seizures themselves also may interrupt sleep, leading to poorly restorative sleep and EDS."

"Patients having nocturnal seizures show reduced sleep efficiency, increased time to first REM period, and increased drowsiness on the MWT.52"

"Most of the older AEDs reduce REM and slow wave sleep, shorten sleep latency, and increase the percentage of Stage 1 and 2 NREM sleep.53"

The problem with snippets is they are easy to take out of context. I recommend reading the section. It is a couple of paragraphs.

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