Welcome back, @donnelson,
I can imagine you must be quite worried, but we’re so glad to hear from you again. Thank you for reaching out to the Connect community.
I’d like to introduce you to @BuckyFestoon @giddyup1 @robertjohn @hamhock, in this Connect discussion, “Prostate Cancer,” http://mayocl.in/2nYLGbQ, with the hope they will return with some insight for you.
From my research, it seems that bicalutamide (Casodex), is part of hormone therapy, and one of the medications known as anti-androgens, which prevent testosterone from reaching your cancer cells; you can read more, here: http://mayocl.in/2oXbG8j
And, here is more information about a team of researchers from Mayo Clinic whose findings may have important implications for men who have a rising prostate-specific antigen (PSA) test: http://mayocl.in/2pjhKrn
@donnelson, what does your doctor say about the PSA level rising again?
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I have been using my Urologist only and he sent me to an Oncologist whom I met with yesterday. My PSA which had been as high as 350 and then nearly 0, after Lupron began to rise again. It is now 32. She has decided that the cancer is probably not responding to the Lupron (I've had 2 shots and am scheduled for another in August.) I am taking Trospium Chloride, Bicalutamide as well as the doxazosin Oxybutynin. She says the next step is Zytiga, which is evidently as costly as $12,000, along with Prednisone. I will take this as well as the others including Lupron. I wondered why I was sent to the financial counsellor which is understandable when you consider the cost of the drug. The next step if this doesn't work is chemo.
My cancer is evidently castration-resistant.
Any one have a similar situation and have done the Zytiga/prednisone regimen?